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Protein-coding gene in the species Homo sapiens

RGS19

RGS19
All data from the card 18
Aliases
RGS19, GAIP, RGSGAIP, regulator of G-protein signaling 19, regulator of G protein signaling 19
External IDs
OMIM: 605071; MGI: 1915153; GeneCards: RGS19
PDB
Ortholog search: PDBe RCSB
Chr.
Chromosome 20 (human)
Band
20q13.33
End
64,079,988 bp
Chr.
Chromosome 2 (mouse)
Band
2 H4|2 103.72 cM
End
181,335,770 bp
BioGPS
More reference expression data
Databases
NCBI: entry; OMA: entry
Species
Human
Entrez
10287
Ensembl
ENSG00000171700
UniProt
P49795
RefSeq (mRNA)
NM_001039467NM_005873
RefSeq (protein)
NP_001034556NP_005864
Location (UCSC)
Chr 20: 64.07 – 64.08 Mb

Regulator of G-protein signaling 19 is a protein that in humans is encoded by the RGS19 gene.

G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase-activating protein that functions to down-regulate Galpha i/Galpha q-linked signaling.

Interactions

RGS19 has been shown to interact with GNAO1, GIPC1, OSTM1, GNAI1, GNAI3 and GNAZ.

References

Further reading

  • RGS19 human gene location in the UCSC Genome Browser.
  • RGS19 human gene details in the UCSC Genome Browser.

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Text from Wikipedia, CC BY-SA 4.0 · Source article