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genyn codio-protien yn y rhywogaeth Homo sapiens

RGS19

RGS19
All data from the card 12
PDB
Human UniProt search: PDBe RCSB
Cyfenwau
RGS19, GAIP, RGSGAIP, regulator of G-protein signaling 19, regulator of G protein signaling 19
Dynodwyr allanol
OMIM: 605071 HomoloGene: 23320 GeneCards: RGS19
Gweithrediad moleciwlaidd
• GO:0005097, GO:0005099, GO:0005100 GTPase activator activity• GO:0001948, GO:0016582 protein binding• G-protein alpha-subunit binding• GO:0006184 GTPase activity
Cydrannau o'r gell
• cytoplasm• Golgi apparatus• bilen• brush border• heterotrimeric G-protein complex• membrane raft• clathrin-coated vesicle• GO:0016023 cytoplasmic vesicle• cellbilen
Species
Bod dynol
Entrez
10287
Ensembl
ENSG00000171700
UniProt
P49795
RefSeq (mRNA)
NM_001039467NM_005873
RefSeq (protein)
NP_001034556NP_005864
Lleoliad (UCSC)
n/a

Protein sy'n cael ei godio yn y corff dynol gan y genyn RGS19 yw RGS19 a elwir hefyd yn Regulator of G protein signaling 19 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 20, band 20q13.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RGS19.

  • GAIP
  • RGSGAIP

Llyfryddiaeth

  • "RGS19 stimulates cell proliferation by deregulating cell cycle control and enhancing Akt signaling. ". Cancer Lett. 2011. PMID 21705135.
  • "Solution structure of human GAIP (Galpha interacting protein): a regulator of G protein signaling. ". J Mol Biol. 1999. PMID 10452897.
  • "RGS19 converts iron deprivation stress into a growth-inhibitory signal. ". Biochem Biophys Res Commun. 2015. PMID 26116529.
  • "5-HT1A receptor-mediated phosphorylation of extracellular signal-regulated kinases (ERK1/2) is modulated by regulator of G protein signaling protein 19. ". Cell Signal. 2014. PMID 24793302.
  • "Elevated expression of RGS19 impairs the responsiveness of stress-activated protein kinases to serum.". Mol Cell Biochem. 2012. PMID 22045062.

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