Protein-coding gene in the species Homo sapiens

ARFRP1

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Aliases: ARFRP1, ARL18, ARP, Arp1, ADP ribosylation factor related protein 1
External IDs: OMIM: 604699; MGI: 1923938; GeneCards: ARFRP1
Chr.: Chromosome 20 (human)
Band: 20q13.33
End: 63,708,025 bp
Chr.: Chromosome 2 (mouse)
Band: 2|2 H4
End: 181,007,197 bp
BioGPS: More reference expression data
Databases: NCBI: entry; OMA: entry
Species: Human
Entrez: 10139
Ensembl: ENSG00000101246
UniProt: Q13795
RefSeq (mRNA): NM_001134758NM_001267544NM_001267545NM_001267546NM_001267547NM_001267548NM_001267549NM_003224
RefSeq (protein): NP_001128230NP_001254473NP_001254474NP_001254475NP_001254476NP_001254477NP_001254478NP_003215NP_001254476.1
Location (UCSC): Chr 20: 63.7 – 63.71 Mb

ADP-ribosylation factor-related protein 1 is a protein that in humans is encoded by the ARFRP1 gene.

Function

The protein encoded by this gene is a membrane-associated GTP-ase and localizes to the plasma membrane. It is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) genes. The gene is located in a gene cluster that includes the a gene (M68) that is overexpressed in some tumors.