genyn codio-protien yn y rhywogaeth Homo sapiens

RGS17

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All data from the card 13

PDB: Human UniProt search: PDBe RCSB
Cyfenwau: RGS17, RGS-17, RGSZ2, hregulator of G-protein signaling 17, regulator of G protein signaling 17
Dynodwyr allanol: OMIM: 607191 HomoloGene: 8242 GeneCards: RGS17
Gweithrediad moleciwlaidd: • GO:0001948, GO:0016582 protein binding• GO:0005097, GO:0005099, GO:0005100 GTPase activator activity• GO:0006184 GTPase activity
Cydrannau o'r gell: • cytoplasm• neuron projection• cell junction• synapse• bilen• cnewyllyn cell• cellbilen• GO:0016023 cytoplasmic vesicle
Prosesau biolegol: • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity• negative regulation of signal transduction• response to amphetamine• G protein-coupled receptor signaling pathway
Species: Bod dynol
Entrez: 26575
Ensembl: ENSG00000091844
UniProt: Q9UGC6
RefSeq (mRNA): NM_012419
RefSeq (protein): NP_036551
Lleoliad (UCSC): n/a

Protein sy'n cael ei godio yn y corff dynol gan y genyn RGS17 yw RGS17 a elwir hefyd yn Regulator of G protein signaling 17 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6q25.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RGS17.

RGSZ2
RGS-17
hRGS17

Llyfryddiaeth

"Altered expression and function of regulator of G-protein signaling-17 (RGS17) in hepatocellular carcinoma. ". Cell Signal. 2011. PMID 21620966.
"Regulators of G-Protein signaling RGS10 and RGS17 regulate chemoresistance in ovarian cancer cells. ". Mol Cancer. 2010. PMID 21044322.
"Variation in regulator of G-protein signaling 17 gene (RGS17) is associated with multiple substance dependence diagnoses. ". Behav Brain Funct. 2012. PMID 22591552.
"Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. ". Clin Cancer Res. 2009. PMID 19351763.
"miR-203 inhibits cell proliferation, invasion, and migration of non-small-cell lung cancer by downregulating RGS17.". Cancer Sci. 2017. PMID 28921827.