Klinefelter syndrome (KS), dem sanso know as 47,XXY, be a chromosome anomaly wer a male get an extra X chromosome. De complications commonly dey include infertility den small, poorly functioning testicles (if present). Dem often dey notice dese symptoms at puberty per, although dis be one of de most common chromosomal disorders. De birth prevalence of KS insyd de State of Victoria, Australia na dem estimate am to be 223 per 100,000 males. Na dem name am after American endocrinologist Harry Klinefelter, wey identify de condition insyd de 1940s, along plus ein colleagues at Massachusetts General Hospital.
De syndrome be defined by de presence of at least one extra X chromosome in addition to a Y chromosome, wey dey yield a total of 47 anaa more chromosomes rada dan de usual 46. Klinefelter syndrome dey occur randomly. De second X chromosome dey cam from de poppie den mommie nearly equally. An older mommie fi get a slightly increased risk of a kiddie plus KS. De syndrome be diagnosed by de genetic test dem know as karyotyping.
Read further
- Cover VI (2012). Living with Klinefelter Syndrome, Trisomy X and 47,XYY: A Guide for Families and Individuals Affected by Extra X and Y Chromosomes (PDF). Virginia Isaacs Cover. ISBN 978-0-615-57400-4.
