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Protein-coding gene in humans

MCOLN2

MCOLN2
All data from the card 17
Aliases
MCOLN2, TRP-ML2, TRPML2, mucolipin 2, mucolipin TRP cation channel 2
External IDs
OMIM: 607399; MGI: 1915529; GeneCards: MCOLN2
Chr.
Chromosome 1 (human)
Band
1p22.3
End
84,997,113 bp
Chr.
Chromosome 3 (mouse)
Band
3|3 H2
End
145,901,268 bp
BioGPS
n/a
Databases
NCBI: entry; OMA: entry
Species
Human
Entrez
255231
Ensembl
ENSG00000153898
UniProt
Q8IZK6
RefSeq (mRNA)
NM_153259NM_001330647
RefSeq (protein)
NP_001317576NP_694991
Location (UCSC)
Chr 1: 84.93 – 85 Mb

Mucolipin-2 also known as TRPML2 (transient receptor potential cation channel, mucolipin subfamily, member 2) is a protein that in humans is encoded by the MCOLN2 gene. It is a member of the small family of the TRPML channels, a subgroup of the large protein family of TRP ion channels.

TRPML2 is associated with the Arf6-regulated trafficking pathway and is involved in the intracellular transport of membranes and membrane proteins.

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Text from Wikipedia, CC BY-SA 4.0 · Source article