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Protein-coding gene in the species Homo sapiens

GSK3A

GSK3A
All data from the card 20
Aliases
GSK3A, Gsk3a, 2700086H06Rik, glycogen synthase kinase 3 alpha
External IDs
OMIM: 606784; MGI: 2152453; GeneCards: GSK3A
PDB
Ortholog search: PDBe RCSB
2.7.11.1
↗
2.7.11.26
↗
Chr.
Chromosome 19 (human)
Band
19q13.2
End
42,242,625 bp
Chr.
Chromosome 7 (mouse)
Band
7|7 A3
End
24,937,276 bp
BioGPS
More reference expression data
Databases
NCBI: entry; OMA: entry
Species
Human
Entrez
2931
Ensembl
ENSG00000105723
UniProt
P49840
RefSeq (mRNA)
NM_019884
RefSeq (protein)
NP_063937
Location (UCSC)
Chr 19: 42.23 – 42.24 Mb

Glycogen synthase kinase-3 alpha is an enzyme that in humans is encoded by the GSK3A gene.

Glycogen synthase kinase 3-alpha EC 2.7.1.37 is a multifunctional protein serine kinase, homologous to Drosophila 'shaggy' (zeste-white3) and implicated in the control of several regulatory proteins including glycogen synthase and various transcription factors (e.g., JUN). It also plays a role in the WNT and phosphoinositide 3-kinase (especially PIK3CG) signaling pathways.

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Text from Wikipedia, CC BY-SA 4.0 · Source article