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Protein-coding gene in the species Homo sapiens

ILKAP

ILKAP
All data from the card 18
Aliases
ILKAP, ILKAP2, ILKAP3, PP2C-DELTA, PPM1O, ILK associated serine/threonine phosphatase, PP2CD
External IDs
MGI: 1914694; GeneCards: ILKAP
3.1.3.16
↗
Chr.
Chromosome 2 (human)
Band
2q37.3
End
238,203,708 bp
Chr.
Chromosome 1 (mouse)
Band
1|1 D
End
91,398,815 bp
BioGPS
More reference expression data
Databases
NCBI: entry; OMA: entry
Species
Human
Entrez
80895
Ensembl
ENSG00000132323
UniProt
Q9H0C8
RefSeq (mRNA)
NM_030768NM_176799
RefSeq (protein)
NP_110395
Location (UCSC)
Chr 2: 238.17 – 238.2 Mb

Integrin-linked kinase-associated serine/threonine phosphatase 2C is an enzyme that in humans is encoded by the ILKAP gene.

The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.

Interactions

ILKAP has been shown to interact with Integrin-linked kinase.

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Text from Wikipedia, CC BY-SA 4.0 · Source article