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Protein-coding gene in the species Homo sapiens

GOLGA4

GOLGA4
All data from the card 18
Aliases
GOLGA4, CRPF46, GCP2, GOLG, MU-RMS-40.18, golgin A4, Trans-GolgiI p230, Golgin 245, p230
External IDs
OMIM: 602509; MGI: 1859646; GeneCards: GOLGA4
PDB
Ortholog search: PDBe RCSB
Chr.
Chromosome 3 (human)
Band
3p22.2
End
37,366,879 bp
Chr.
Chromosome 9 (mouse)
Band
9|9 F3
End
118,582,519 bp
BioGPS
n/a
Databases
NCBI: entry; OMA: entry
Species
Human
Entrez
2803
Ensembl
ENSG00000144674
UniProt
Q13439Q49A56
RefSeq (mRNA)
NM_001172713NM_002078
RefSeq (protein)
NP_001166184NP_002069NP_001166184.1NP_002069.2
Location (UCSC)
Chr 3: 37.24 – 37.37 Mb

Golgin subfamily A member 4 is a protein that in humans is encoded by the GOLGA4 gene.

The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The golgins are a family of proteins, of which the protein encoded by this gene is a member, that are localized to the Golgi. This protein has been postulated to play a role in Rab6-regulated membrane-tethering events in the Golgi apparatus. Alternative splice variants have been described but their full-length nature has not been determined.

Interactions

GOLGA4 has been shown to interact with ARL1.

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Text from Wikipedia, CC BY-SA 4.0 · Source article