Risperidone, dem sell under de brand name Risperdal among odas, be an atypical antipsychotic dem use to treat schizophrenia den bipolar disorder, as well as aggressive den self-injurious behaviors wey be associated plus autism spectrum disorder. Dem dey take am either by mouth anaa by injection (i.e., subcutaneous anaa intramuscular). De injectable versions be long-acting den dey last for 2–4 weeks.
Common side effects dey include weight gain, drowsiness, fatigue, insomnia, dry mouth, constipation, elevated prolactin levels, den restlessness. Serious side effects fi include de potentially permanent movement disorder tardive dyskinesia, as well as neuroleptic malignant syndrome, an increased risk of suicide, den high blood sugar levels. Insyd older people plus psychosis as a result of dementia, e fi increase de risk of death. E be unknown if e be safe for use insyd pregnancy. Ein mechanism of action no be entirely clear, buh dem dey believe to be related to ein action as a dopamine den serotonin antagonist.
Study of risperidone begin insyd de late 1980s wey dem approve for sale insyd de United States insyd 1993. E be on de World Health Organization's List of Essential Medicines. E be available as a generic medication. Insyd 2023, e be de 176th most commonly prescribed medication insyd de United States, plus more dan 2 million prescriptions.
Read further
- Dean L (2017). "Risperidone Therapy and CYP2D6 Genotype". In Pratt VM, McLeod HL, Rubinstein WS, et al. (eds.). Medical Genetics Summaries. National Center for Biotechnology Information (NCBI). PMID 28520384. Bookshelf ID: NBK425795.