factograf
EN
Sign in

Protein-coding gene in the species Homo sapiens

SAV1

SAV1
All data from the card 18
Aliases
SAV1, SAV, WW45, WWP4, salvador family WW domain containing protein 1
External IDs
OMIM: 607203; MGI: 1927144; GeneCards: SAV1
PDB
Ortholog search: PDBe RCSB
Chr.
Chromosome 14 (human)
Band
14q22.1
End
50,668,306 bp
Chr.
Chromosome 12 (mouse)
Band
12|12 C2
End
70,033,776 bp
BioGPS
n/a
Databases
NCBI: entry; OMA: entry
Species
Human
Entrez
60485
Ensembl
ENSG00000151748
UniProt
Q9H4B6
RefSeq (mRNA)
NM_021818
RefSeq (protein)
NP_068590
Location (UCSC)
Chr 14: 50.63 – 50.67 Mb

Protein salvador homolog 1 is a protein that in humans is encoded by the SAV1 gene.

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a coiled-coil region. It is ubiquitously expressed in adult tissues. The encoded protein is 94% identical to the mouse protein at the amino acid level.

Read next

In 3 languages

Text from Wikipedia, CC BY-SA 4.0 · Source article