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Protein-coding gene in the species Homo sapiens

RAP2B

RAP2B
All data from the card 19
Aliases
RAP2B, member of RAS oncogene family
External IDs
OMIM: 179541; MGI: 1921262; GeneCards: RAP2B
PDB
Ortholog search: PDBe RCSB
3.6.5.2
↗
Chr.
Chromosome 3 (human)
Band
3q25.2
End
153,170,627 bp
Chr.
Chromosome 3 (mouse)
Band
3|3 E1
End
61,275,851 bp
BioGPS
More reference expression data
Databases
NCBI: entry; OMA: entry
Species
Human
Entrez
5912
Ensembl
ENSG00000181467
UniProt
P61225
RefSeq (mRNA)
NM_002886
RefSeq (protein)
NP_002877
Location (UCSC)
Chr 3: 153.16 – 153.17 Mb

Ras-related protein Rap-2b is a protein that in humans is encoded by the RAP2B gene. RAP2B belongs to the Ras-related protein family.

This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated.

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Text from Wikipedia, CC BY-SA 4.0 · Source article