Function
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.
Interactions
PARD6B has been shown to interact with:
- CDC42,
- Protein kinase Mζ,
- RAC1, and
- RHOQ.
