M6

• Groupe M6, a French media holding company
  • M6 (TV channel), a French television channel
• Mike & The Mechanics (1999 album), by Mike & The Mechanics
• "M6", a song on the album Centralia by the metal band Car Bomb

• M6 bayonet, a bayonet for the M14 rifle
• M6 bomb service truck, a truck used to move bombs during World War II
• M6 gun motor carriage, an American World War II light truck armed with an anti-tank gun
• M6 gun, a 3" towed artillery piece
• M6 heavy tank, a World War II heavy tank design that never entered full production
• M6 Linebacker, an anti-aircraft variant of the M2 Bradley infantry fighting vehicle
• M6 mine, a United States metal-cased, circular anti-tank landmine
• C15TA armoured truck (Danish designation: M6 Mosegris)
• M6 tractor, a high-speed artillery tractor
• M6 mortar, a 60mm mortar used by the British Army
• Hirtenberger M6C-210 Commando, a 60mm mortar used by various armies
• LWRC M6, a series of US military carbines based on the M4 carbine
• Fokker M.6, a 1916 German two-seat experimental fighter aircraft
• Macchi M.6, a 1917 Italian flying boat fighter prototype

Survival guns

• M6 aircrew survival weapon, a.22 Hornet over.410 gauge combination gun
• Springfield Armory M6 Scout, a.22 LR over.410 gauge combination gun
• Chiappa M6 survival gun, a 12 gauge over.22 LR combination gun

• Butterfly Cluster (catalogued as Messier 6 or M6), an open star cluster in the constellation Scorpius
• M6 (cipher), a block cipher used by Digital Transmission Content Protection
• M6, a British peak programme meter standard used for measuring the volume of audio broadcasts
• Meizu M6 miniPlayer, flash-based portable media player
• M6, one of the 1N400x rectifier diodes
• Apple M6, a system on a chip
• Leica M6, a rangefinder camera once popular among photojournalists
• Canon EOS M6, a mirrorless digital camera
• SureFire M6 Guardian, a flashlight
• M6, an ISO metric screw thread

Automobiles

• BMW M6, a high-performance 6 Series automobile
• BYD M6 (2010), a minivan
• BYD M6 (2024), electric version of the BYD Song Max MPV
• BMW M30 or M06, a 1968 straight-6 engine
• M6 Presto-Matic, a semi-automatic transmission made by Chrysler
• McLaren M6A, a racing car built by McLaren for the Can-Am series
• Haima M6, a saloon
• Haval M6, an SUV
• Refine M6, an MPV
• Trumpchi M6, an MPV

Aviation

• Amerijet International (IATA airline designator: M6), a cargo airline based in the US
• Havre de Grace Seaplane Base (FAA LID: M06)
• Miles M.6 Hawcon, a 1930s British experimental monoplane
• M-6 aero-engine, a 1920 Soviet copy of the Hispano-Suiza 8Fb V-8 aero engine

Public transport

• Bucharest Metro Line M6, a planned metro line of the Bucharest Metro
• M6 (New York City bus), a former New York City Bus route in Manhattan
• M6 (Istanbul Metro), a short metro line in Istanbul, Turkey
• Sri Lanka Railways M6, a diesel-electric locomotive used in Sri Lanka
• M6 (railcar), a Metro-North Railroad railcar

Roads

• Frederik Meijer Trail, formerly the M-6 Trail, a bike trail running along the M-6 freeway in the Grand Rapids, Michigan area, US
• Highway M06 (Ukraine), a road in Ukraine
• M6 motorway, a motorway in the UK
  • M6 Toll, a toll motorway which relieves traffic on the neighbouring M6
• M-6 (Michigan highway), a state highway in the Grand Rapids, Michigan area, US
• M6 highway (Russia), linking Moscow to the Caspian Sea
• M6 motorway (Hungary), a north–south motorway connecting Budapest to Pécs and Croatia
• M6 motorway (Ireland), a motorway forming part of the N6 Dublin to Galway national primary route
• M6 road (Zambia), in Zambia
• M6 road (Malawi), in Malawi
• M6 Motorway (Sydney), a proposed motorway in New South Wales, Australia

South Africa

• M6 (Cape Town), a Metropolitan Route in Cape Town
• M6 (Johannesburg), a Metropolitan Route in Johannesburg
• M6 (Pretoria), a Metropolitan Route in Pretoria
• M6 (Gqeberha), a Metropolitan Route in Gqeberha/Port Elizabeth

Other transport

• Ursynów M-6, a prototype hovercraft

• Mark Sixma (born 1983), Dutch trance and house producer
• Mohammed VI of Morocco (born 1963), King of Morocco
• Raúl Meza Ontiveros (1966–2007), Mexican suspected drug lord, nicknamed "M6"

• M6, a difficulty grade in mixed climbing
• MLBB M6 World Championship, the sixth Mobile Legends: Bang Bang World Championship held in 2024