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Protein-coding gene in humans

KIF2C

KIF2C
All data from the card 18
Aliases
KIF2C, CT139, KNSL6, MCAK, kinesin family member 2C
External IDs
OMIM: 604538; MGI: 1921054; GeneCards: KIF2C
PDB
Ortholog search: PDBe RCSB
Chr.
Chromosome 1 (human)
Band
1p34.1
End
44,767,767 bp
Chr.
Chromosome 4 (mouse)
Band
4 D1|4 53.42 cM
End
117,039,836 bp
BioGPS
More reference expression data
Databases
NCBI: entry; OMA: entry
Species
Human
Entrez
11004
Ensembl
ENSG00000142945
UniProt
Q99661
RefSeq (mRNA)
NM_001297655NM_001297656NM_001297657NM_006845
RefSeq (protein)
NP_001284584NP_001284585NP_001284586NP_006836
Location (UCSC)
Chr 1: 44.74 – 44.77 Mb
A ribbon and surface diagram of the KIF2C motor domain. The kinesin structure is pseudo-colored to highlight the ATPase site with a bound nucleotide. The figure then presents KIF2C binding to the tubulin dimer and finally visualizes a KIF2C motor head in the…
A ribbon and surface diagram of the KIF2C motor domain. The kinesin structure is pseudo-colored to highlight the ATPase site with a bound nucleotide. The figure then presents KIF2C binding to the tubulin dimer and finally visualizes a KIF2C motor head in the…

Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene.

The protein encoded by this gene is a member of kinesin-like protein family, and contains common ATPase site structures such as the P-loop, Switch 1, and Switch 2. Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation.

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