HS

• HS Produkt, a Croatian firearms manufacturer
• Helsingin Sanomat, a newspaper in Finland
• Hawker Siddeley, aircraft manufacturing group
• Henschel & Son, in aircraft prefixes; e.g., Hs 117
• Head & Shoulders or H&S, a shampoo brand
• Harris Scarfe and HS Home, a chain of Australian department stores

Chemistry

• Hassium, symbol Hs, a chemical element
• Humic substance
• Bisulfide, HS⁻, a chemical compound derived from H₂S
• Mercapto radical, HS^•, a radical molecule
• Hun stuff (a World War I name for mustard gas)

Medicine

• hs, medical abbreviation for "hours of sleep"
• h.s., medical abbreviation for the Latin phrase hora somni ("at bedtime")
• Hereditary spherocytosis, a genetic disorder marked by hemolytic anemia
• Hidradenitis suppurativa, a skin condition affecting apocrine sweat glands and hair follicles

Other uses in science and technology

• '.hs', the Haskell programming language's typical filename extension
• Heat sink
• Higman–Sims group, in mathematics
• , the Hilbert–Schmidt norm
• Hilbert series of a graded algebra
• Horizon scanning, a method from futures studies
• Hypothetical syllogism, a proof rule in classical logic

• Curtiss HS, an American patrol flying boat
• Lexus HS, a Japanese compact hybrid sedan
• MG HS, a Chinese-British compact SUV
• YTHS HS, a Chinese unmanned aerial vehicle series

• Harlem Spartans, a British hip hop collective
• Harmonized System, the Harmonized Commodity Description and Coding System of tariff nomenclature
• High school (secondary education)
• Holy Spirit
• HS postcode area, covering the Outer Hebrides, Scotland
• Sestertius, an ancient Roman coin
• Solar Hijri calendar (= Hijri Shamsi)
• SS-Heimatschutz Slowakei (HS), a German paramilitary group in Slovakia during World War II
• Thailand (aircraft registration prefix HS)