Protein-coding gene in the species Homo sapiens

FNBP1

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Aliases: FNBP1, FBP17, formin binding protein 1
External IDs: OMIM: 606191; MGI: 109606; GeneCards: FNBP1
PDB: Ortholog search: PDBe RCSB
Chr.: Chromosome 9 (human)
Band: 9q34.11
End: 130,043,194 bp
Chr.: Chromosome 2 (mouse)
Band: 2|2 B
End: 31,032,020 bp
BioGPS: More reference expression data
Databases: NCBI: entry; OMA: entry
Species: Human
Entrez: 23048
Ensembl: ENSG00000187239
UniProt: Q96RU3
RefSeq (mRNA): NM_015033NM_001363755
RefSeq (protein): NP_055848NP_001350684
Location (UCSC): Chr 9: 129.89 – 130.04 Mb

Formin-binding protein 1 is a protein that in humans is encoded by the FNBP1 gene.

Function

The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human.