factograf
EN
Sign in

Protein-coding gene in humans

ETS2

ETS2
All data from the card 18
Aliases
ETS2, ETS2IT1, ETS proto-oncogene 2, transcription factor
External IDs
OMIM: 164740; MGI: 95456; GeneCards: ETS2
PDB
Ortholog search: PDBe RCSB
Chr.
Chromosome 21 (human)
Band
21q22.2
End
38,824,955 bp
Chr.
Chromosome 16 (mouse)
Band
16 C4|16 56.64 cM
End
95,522,095 bp
BioGPS
More reference expression data
Databases
NCBI: entry; OMA: entry
Species
Human
Entrez
2114
Ensembl
ENSG00000157557
UniProt
P15036
RefSeq (mRNA)
NM_001256295NM_005239
RefSeq (protein)
NP_001243224NP_005230
Location (UCSC)
Chr 21: 38.81 – 38.82 Mb

ETS2 is a gene that in humans is encoding the C-ETS2 protein. The protein encoded by this gene belongs to the ETS family of transcription factors. It has been found to play a key role in the development of inflammatory bowel disease.

Interactions

ETS2 has been shown to interact with:

Clinical significance

ETS2 has been linked to a variety of diseases, including Takayasu's arteritis, inflammatory bowel disease, primary sclerosing cholangitis, and ankylosing spondylitis, all associated with a region on chromosome 21 at 21q22.

Read next

In 7 languages

Text from Wikipedia, CC BY-SA 4.0 · Source article