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Chemical compound

Apraclonidine

Apraclonidine
All data from the card 24
Trade names
Iopidine, others
Other names
Apraclonidine hydrochloride (JAN JP), Apraclonidine hydrochloride (USAN US)
AHFS/Drugs.com
Monograph
MedlinePlus
a608005
License data
US DailyMed: Apraclonidine
Routes ofadministration
Ophthalmic administration
ATC code
S01EA03 (WHO)
Legal status
UK: POM (Prescription only) US: ℞-only / OTC In general: ℞ (Prescription only)
Protein binding
98.7%
Elimination half-life
8 hours
CAS Number
66711-21-573218-79-8
PubChem CID
221651763
IUPHAR/BPS
7117
DrugBank
DB00964
ChemSpider
2130
UNII
843CEN85DID2VW67N38H
KEGG
D07461D01008
ChEBI
CHEBI:2788
ChEMBL
ChEMBL647
CompTox Dashboard (EPA)
DTXSID1048415
ECHA InfoCard
100.164.104
Formula
C9H10Cl2N4
Molar mass
245.11 g·mol−1
3D model (JSmol)
Interactive image

Apraclonidine (INN), sold under the brand name Iopidine among others, is a medication used for the treatment of intraocular pressure. It is an alpha-adrenergic agonist. It is used as the salt apraclonidine hydrochloride. It is given by ophthalmic administration.

Medical uses

Apraclonidine is indicated to control or prevent post-surgical elevations in intraocular pressure that occur in people after argon laser trabeculoplasty, argon laser iridotomy, or Nd:YAG posterior capsulotomy.

Society and culture

Apraclonidine was approved for medical use in the United States in 1987.

Names

Apraclonidine is sold under the brand names Iopidine and Brytly.

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Text from Wikipedia, CC BY-SA 4.0 · Source article