ASE

• Academia de Studii Economice (the Economic Sciences Academy), in Bucharest, Romania
• Admiralty Signal Establishment, a former defense research organization in the UK
• ASE Group (Advanced Semiconductor Engineering),
• African School of Economics, a private university located in Benin
• Agence spatiale européenne, the French name for European Space Agency
• Alliance to Save Energy, a non-profit coalition in Washington, D.C., US
• Amalgamated Society of Engineers
• American Society of Echocardiography
• Amity School of Engineering, a private engineering college located in Noida, India
• The Association for Science Education, a professional association in the United Kingdom for teachers of science
• Association for Social Economics, an international association dedicated to social economics
• Association of Space Explorers, a non-governmental space organization of international astronauts
• Atomstroyexport, the Russian nuclear power equipment and service export monopoly
• Auslands- und Spezialeinsätze, a specialised police unit within the Federal Criminal Police Office (Germany)
• Australian Screen Editors, an Australian film editing guild headquartered in Sydney
• Automotive Service Excellence, a U.S.-based group to improve the quality of automobile servicing

Stock exchanges

• Ahmedabad Stock Exchange, the second oldest exchange in India
• Alberta Stock Exchange, a defunct stock exchange in Calgary
• American Stock Exchange, now known as NYSE American
• Amman Stock Exchange, the Jordanian stock exchange
  • ASE Market Capitalization Weighted Index, a stock index of the Amman Stock Exchange in Jordan
• Athens Stock Exchange, the Greek stock exchange
• Australian Securities Exchange

• Accelerated solvent extraction, a method for extracting chemicals from a matrix
• Amplified spontaneous emission or superluminescence
• Advanced silicon etching, a deep reactive ion etching

Computing

• Adaptive Server Enterprise, a database product from Sybase
• Android Scripting Environment, now known as Scripting Layer for Android
• Application-specific extensions, supplemental optional architectural extensions in the MIPS architecture
• Applied Systems Engineering
• ASCII Scene Export, a file format originated in 3D Studio
• The All-Seeing Eye, an application to help Internet gamers find game servers

• Anatomical Sciences Education, an academic journal
• Anglo-Saxon England (journal), an academic journal
• Armed Services Editions (ACEs), a paperback book format used during World War II

• Aspen–Pitkin County Airport (IATA airport code)
• American Silver Eagle, an American bullion coin for precious-metal investors
• International Conference on Automated Software Engineering, an academic conference
• American Sign Language ISO code