genyn codio-protien yn y rhywogaeth Homo sapiens

VPS28

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All data from the card 11

Cyfenwau: VPS28, ESCRT-I subunit, VPS28 subunit of ESCRT-I
Dynodwyr allanol: OMIM: 611952 HomoloGene: 69205 GeneCards: VPS28
Gweithrediad moleciwlaidd: • GO:0032403 protein-containing complex binding• ubiquitin binding• GO:0001948, GO:0016582 protein binding
Cydrannau o'r gell: • cytoplasm• cytosol• endosome• bilen• late endosome membrane• cellbilen• early endosome• endosome membrane• extracellular exosome• ESCRT I complex• host cell
Species: Bod dynol
Entrez: 51160
Ensembl: ENSG00000160948ENSG00000285339
UniProt: Q9UK41Q548N1
RefSeq (mRNA): NM_016208NM_183057
RefSeq (protein): NP_057292NP_898880NP_057292.1
Lleoliad (UCSC): n/a

Protein sy'n cael ei godio yn y corff dynol gan y genyn VPS28 yw VPS28 a elwir hefyd yn VPS28, ESCRT-I subunit a Vacuolar protein sorting 28 (Yeast), isoform CRA_a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 8, band 8q24.3.

Llyfryddiaeth

"Solution structure of the ESCRT-I complex by small-angle X-ray scattering, EPR, and FRET spectroscopy. ". Proc Natl Acad Sci U S A. 2011. PMID 21596998.
"YPXL/I is a protein interaction motif recognized by aspergillus PalA and its human homologue, AIP1/Alix. ". Mol Cell Biol. 2003. PMID 12588984.
"Protein sorting into multivesicular endosomes. ". Curr Opin Cell Biol. 2003. PMID 12892785.
"Equine infectious anemia virus utilizes host vesicular protein sorting machinery during particle release. ". J Virol. 2003. PMID 12857913.
"CIIA negatively regulates the Ras-Erk1/2 signaling pathway through inhibiting the Ras-specific GEF activity of SOS1.". J Cell Sci. 2014. PMID 24522193.

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VPS28

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