genyn codio-protien yn y rhywogaeth Homo sapiens

MPDZ

1 min read
In 8 languages

All data from the card 12

PDB: Human UniProt search: PDBe RCSB
Cyfenwau: MPDZ, HYC2, MUPP1, multiple PDZ domain crumbs cell polarity complex component
Dynodwyr allanol: OMIM: 603785 HomoloGene: 2841 GeneCards: MPDZ
Gweithrediad moleciwlaidd: • protein C-terminus binding• GO:0001948, GO:0016582 protein binding
Prosesau biolegol: • cell adhesion• GO:0022415 viral process
Species: Bod dynol
Entrez: 8777
Ensembl: ENSG00000107186
UniProt: O75970
RefSeq (mRNA): NM_001261406NM_001261407NM_003829NM_001330637
RefSeq (protein): NP_001248335NP_001248336NP_001317566NP_003820NP_001362342NP_001362345NP_001362346NP_001362347NP_001362348NP_001362349NP_001362350NP_001362351NP_001362352NP_001362353NP_001362354NP_001362355NP_001362356NP_001365707
Lleoliad (UCSC): n/a

Protein sy'n cael ei godio yn y corff dynol gan y genyn MPDZ yw MPDZ a elwir hefyd yn Multiple PDZ domain protein a Multiple PDZ domain crumbs cell polarity complex component (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 9, band 9p23.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MPDZ.

HYC2
MUPP1

Llyfryddiaeth

"Genetic variability in the NMDA-dependent AMPA trafficking cascade is associated with alcohol dependence. ". Addict Biol. 2012. PMID 21762291.
"Structure-based identification of CaMKIIα-interacting MUPP1 PDZ domains and rational design of peptide ligands to target such interaction in human fertilization. ". Amino Acids. 2016. PMID 26984442.
"Evaluating the Association between Keratoconus and Reported Genetic Loci in a Han Chinese Population. ". Ophthalmic Genet. 2015. PMID 25675348.
"The multi-PDZ domain protein-1 (MUPP-1) expression regulates cellular levels of the PALS-1/PATJ polarity complex. ". Exp Cell Res. 2013. PMID 23880463.
"Mutation in MPDZ causes severe congenital hydrocephalus.". J Med Genet. 2013. PMID 23240096.